Publications

 

1) A Concise Route To Tetrahydrophenanethridinones and Functionalised Isoquinolones.  Heaney. H.; Taha, M.O., Synlett, 1996, 820 - 822.

 

2) The oxidation of homophthalimide derivatives by dioxygen in alkaline media and cleavage-cyclisation reactions.  Heaney, H.; Taha, M.O.; Slawin, A.M.Z., Tetrahedron Lett., 1997, 38, 3051-3054.

 

3) The Bis(homoallylic) Stabilisation of an Acyliminium Ion and Reactions with Nucleophiles. Heaney. H.; Taha, M.O., Tetrahedron Lett., 1998, 39, 3341-3344.

 

4) N-Acyliminium ion cyclisation versus rearrangement. The synthesis of 13,13-dimethylberberines and 3,4-dimethylisoquinolin-1-ones, Heaney, H.; Taha, M.O., Tetrahedron Letters, 2000, 41, 1993-1996.

 

5) The oxidation of 3-alkylhomophthalimide derivatives by dioxygen in alkaline media and Bischler-Napieralski reactions of cleavage-cyclization products. Heaney, Harry; Taha, Mutasem O; Arkivoc, 2000, 1(3), 335-351.

 

6) Synthesis of Chitosan Succinate and Chitosan phthalate and Their Evaluation as Suggested Matrices in Orally administered, Colon-Specific Drug Delivery Systems. Aiedeh, K.; Taha, M.O., Archiv Der Pharmazie, 1999, 332, 103-107.

 

7) Synthesis of Chitosan Triethylene Glycol Phthalate and its Evaluation as a Binder in Wet granulation Procedures. Aiedeh, K; Taha, M.O., Die Pharmazie. 1999, 54, 614-619.

 

8) An Investigation on the Suitability of Chitosan-Triethyleneglycol-Phthalate as a Matrix in Prolonged-Release, Orally Administered, Chlorpheniramine Maleate Granules.  Taha, M.O. and Aiedeh, K, Amro, B., STP Pharma Sciences 2000. 10,395-400.

 

9) Synthesis of Iron-Crosslinked Hydroxamated Alginic Acid and its in vitro Evaluation as a Potential Matrix Material for Oral Sustained-Release Beads. Taha, M.O. and Aiedeh, K., Die Pharmazie, 2000, 55, 663-667.

 

10) Spectrophotometric and Conductimetric Study of the Complexation of Ranitidine to Fe⁺², Fe⁺³, Al⁺³, Mg⁺², Cu⁺², Ni⁺² and Pb⁺² Metal ion: Pharmaceutical Implications, Hamdan, I.; Taha, MO., Scientia Pharmazeutica (Sci. Pharm.) 2000, 68, 357-367.

 

11) Synthesis of Iron-Crosslinked Chitosan Succinate and Iron-Crosslinked Hydroxamated Chitosan Succinate and their in vitro Evaluation as Potential Matrix Materials for Oral Theophylline Sustained-Release Beads, Aiedeh, K.; Taha, M.O. European Journal of Pharmaceutical Sciences, 2001, Vol 13/2,   pp 159-168.

 

12) Aiedeh, K.; Taha, M. O.; Sweileh, B.  Testosterone-succinate-dextran and testosterone-succinate-polyvinyl alcohol conjugates: Synthesis and testosterone release in plasma. Acta Technologiae et Legis Medicamenti, 2001, 12(3), 267-281.

 

13) Amro, B. I.; Taha, M. O.; Aiedeh, K.  Evaluation of chitosan-triethyleneglycol-phthalate as a potential matrix for chlorpheniramine maleate controlled-release oral tablets.  Acta Technologiae et Legis Medicamenti  2001, 12(3),  239-252.

 

14) Development of QSPR models for Pseudoternary Microemulsions Formulated with Nonionic Surfactants and Cosurfactants: Application of Data Mining and Molecular Modeling. M. O. Taha; M. Al-Ghazawi; H. Abu-Amara; E. Khalil. European Journal of Pharmaceutical Sciences 2002, 15(5), 461-478

 

15)  In-vitro Alpha-Amylase Inhibitory Effects of Some Clinically Used Drugs. Hamdan, I.; Affifi, F.; Taha, M.O.; Die Pharmazie, 2004, 59 (10), 799-801.

 

16)  Investigation of the Active Constituents of Portulaca Oleraceae L. (Portulacaceae) Growing in Jordan. Rashed, A. N.; Afifi, F. U.; Shaedah, M.; Taha, M. O.; Pakistan Journal of Pharmaceutical Sciences, 2004, 17(1), 37-46.

 

17)Evaluation of Chitosan-Succinate and Chitosan-Phthalate as Enteric Coating Polymers for Diclofenac Sodium Tablets. Aiedeh, K.; Taha, M. O.; Al-Khatib, H.  Drug Delivery Science and Technology (STP Pharma Sciences), 2005, 15 (3), 207-211.

 

18) Ligand-Based Assessment of Factor Xa Binding Site Flexibility via Elaborate Pharmacophore Exploration and Genetic Algorithm-Based QSAR Modeling. Taha, Mutasem O.; Qandil, Amjad M.; Zaki, Dhia D.; Murad A. AlDamen. European Journal of Medicinal Chemistry, 2005, 40(7), 701-727.

 

19)Synthesis of Zinc-Crosslinked Thiolated Alginic acid Beads and their In Vitro Evaluation as Potential Enteric Delivery System Utilizing Folic Acid as Model Drug. Mutasem O. Taha, Khalid M. Aiedeh, Yusef Al-Hiari and Hatim Al-Khatib. Die Pharmazie. 2005, 60, 736-742.

 

20) QSPR Modeling of Pseudoternary Microemulsions Formulated Employing Lecithin Surfactants: Application of Data Mining, Molecular and Statistical Modeling. Mutasem O. Taha, Heba Abdel-Halim, Mutasim Al-Ghazawi, Enam Khalil. International Journal of Pharmaceutics. 2005, 295, 135-155.

 

21) Application of novel chitosan derivatives in the dissolution enhancement of a poorly water soluble drug using spray drying technique. Khalid M. Aiedeh, Hatim Al-Khatib, Mutasem O. Taha, Nizar Al-Zo’by, Die Pharmazie. 2006, 61, 306-311.

 

22)  Effects of variable docking conditions and scoring functions on the qualities of protein aligned CoMFA models constructed from diverse h-PTP 1B inhibitors. Mutasem O. Taha*, Murad AlDhamin. Journal of Medicinal Chemistry. 2005, 48, 8016-8034.

23)Berberine potently inhibits protein tyrosine phosphatase 1B: investigation by docking simulation and experimental validation. Bustanji, Y.; Taha, M. O*.; Yousef, M.; Bakri, AG. Journal of Enzyme Inhibition and Medicinal Chemistry.  2006, 21,163-71.

 

24) Discovery of potent inhibitors of pseudomonal quorum sensing via pharmacophore modeling and in silico screening.  Mutasem O. Taha*, Amal G. Al-Bakri and Waleed A. Zalloum Bioorganic & Medicinal Chemistry Letters, 2006,16, 5902-5906.

 

25)   Synthesis and in vitro behavior of iron-crosslinked N-methyl and N-benzyl hydroxamated derivatives of alginic acid as controlled release carriers. Hatim S. AlKhatib, Mutasem O. Taha, Khaled M. Aiedeh, Yasser Bustanji and Bassam Sweileh. European Polymer Journal, 2006, 42, 2464-2474.

 

26) Discovery of New Potent Human Protein Tyrosine Phosphatase Inhibitors Via Pharmacophore and QSAR Analysis Followed by In-Silico Screening. Mutasem O. Taha*, Yasser Bustanji, Amal G. Al-Bakri, Al-Motassem Yousef, Waleed A. Zalloum, Ihab M. Al-Masri and Naji Atallah. Journal of Molecular Graphics and Modelling,  25 (2007) 870–884

 

27) Effect of Increasing Concentrations of Quinine on the Volatile compounds in Cultured Tissues of Iris atrofusca Baker and Iris petrana Dinsmore. Ahmad H. Al-Ghabesh, Dhia S. Hassawi, Mutasem O. Taha, Fatma U. Afifi. Biotechnology, 25 (2007) 218–224.

 

28) Effect of Ionic Crosslinking on the Drug Release Properties of Chitosan Diacetate Matrices. Khaled M. Aiedeh, Mutasem O. Taha, Yusuf Al-Hiari, Yasser Bustanji, Hatim S. Alkhatib. Journal of Pharmaceutical Sciences, 2007, 96 (1), 38-43.

 

29) Combining Docking, Scoring and Molecular Field Analyses To Probe Influenza Neuraminidase-Ligand Interactions. Areej M. Abu Hammad, Fatima Afifi, Mutasem O. Taha*. Journal of Molecular Graphics and Modelling, 2007. 26, 443–456.

 

30) Sodium Lauryl Sulfate Impedes Drug Release From Zinc-Crosslinked Alginate Beads: Switching From Enteric Coating Release Into Biphasic Profiles. Mutasem O. Taha*, Wissam Nasser, Adel Ardakani, Hatim S. AlKhatib. International Journal of Pharmaceutics, 2008, 350, 291-300

 

31) Discovery of New MurF Inhibitors via Pharmacophore Modeling and QSAR Analysis followed by in-silico screening. Mutasem O. Taha*, Naji Atallah, Amal G. Al-Bakri, Catherine Paradis-Bleau, Hiba Zalloum , Khaled Younis and Roger C. Levesque. Bioorganic and Medicinal Chemistry. 2008, 16, 1218-1235.

 

32) Olanzapine inhibits glycogen synthase kinase-3b: an investigation by docking simulation and experimental validation. Mohammad K. Mohammad, Ihab M. Al-Masri, Mutasem O Taha, Mohamed A. S. Al-Ghussein, Hatim S. AlKhatib, Samer Najjar, Yasser Bustanji. European Journal of Pharmacology, 2008, 584, 185–191.

 

33) Pharmacophore Modeling, Quantitative Structure-Activity Relationship Analysis and In Silico Screening Reveal Potent Glycogen Synthase Kinase-3b Inhibitory Activities for Cimetidine, Hydroxychloroquine and Gemifloxacin. Mutasem O. Taha*, Yasser Bustanji, Mohamed A.S. Al-Ghussein, Mohammad Mohammad, Hiba Zalloum, Ihab M. Al-Masri, Naji Atallah. Journal of Medicinal Chemistry, 2008, 51, 2062–2077.

 

34) Development of Predictive In Silico Model for Cyclosporine- and Aureobasidin-Based P-Glycoprotein Inhibitors Employing Receptor Surface Analysis. Hiba M. Zalloum, Mutasem O. Taha*, Journal of molecular graphics and Modelling, 2008, 27, 439–451

 

35) Inhibition of Glycogen Synthase Kinase by Curcumin: Investigation by Simulated Molecular Docking and Subsequent in vitro/in vivo evaluation. Yasser Bustanji, Mutasem O.Taha, Ihab M. Almasri, Mohamed A.S. Al-Ghussein, Mohammad, K. Mohammad,  and Hatim S. AlKhatib, Journal of Enzyme Inhibition and Medicinal Chemistry. 2008, Accepted, In Press. 

 

36) Combining Ligand-Based Pharmacophore Modeling, QSAR Analysis and In -Silico Screening for the Discovery of New Potent Hormone Sensitive Lipase Inhibitors. Mutasem O. Taha*, Lina A. Dahabiyeh, Yasser Bustanji, Hiba Zalloum, Suheer Saleh. Journal of Medicinal Chemistry, 2008, 51, 6478–6494.

 

37) Discovery of New DPP IV Inhibitors via Pharmacophore Modeling and QSAR Analysis followed by in-silico screening. Ihab M. Al-Masri, Mohammad K. Mohammad, Mutasem O. Taha*. ChemMedChem, 2008, 3, (11), 1763-1779

 

38)       Book Chapter: Ethnopharmacology as an emergent discipline: From empirical knowledge to drug discovery. Talal Aburjai, Rabab Tayyem and Mutasem Taha. ISBN 978-81-308-0213-8.

 

39) Inhibition of dipeptidyl peptidase IV (DPP IV) is one of the mechanisms explaining the hypoglycemic effect of berberine. Ihab M. Al-masri, Mohammad K. Mohammad, Mutasem O. Taha. Journal of Enzyme Inhibition and Medicinal Chemistry. 2009, Accepted, In Press.

 

40) Homology modeling of MCH1 receptor and validation by docking/scoring and protein-aligned CoMFA. Areej Abu-Hammad, Waleed A. Zalloum, Hiba Zalloum, Ghassan Abu-Sheikha, Mutasem O. Taha*. European Journal of Medicinal Chemistry, 2009, 44, 2583–2596.

 

41) Docking simulations and in vitro assay unveil potent inhibitory action of papaverine against protein tyrosine phosphatase 1B. Yasser Bustanji, Mutasem O. Taha, Ihab Mustafa. Almasri, Mohammad Khalil. Mohammad. Biological and Pharmaceutical Bulletin, 2009,32 (4), 640-645.

 

42) Pharmacophore modelling, Quantitative Structure-Activity Relationship Analysis and Shape-Complemented In-Silico Screening Allow Access to Novel Influenza Neuraminidase Inhibitors. Areej M. Abu Hammad, Mutasem O. Taha*. Journal of Chemical Information and Modeling. 2009, 49, 978–996

 

43) Phenytoin Enhances Collagenization in Excision Wounds and Tensile Strength in Incision Wounds. Eyad Qunaibi, Ahmad Disi, Mutasem Taha. Pharmazie, 2009, Accepted, In Press.